Home / Medications / Jakafi

Jakafi patient assistance program

Have you been prescribed Jakafi and need help paying? We may be able to help. With our assistance, you may be able to get your Jakafi for a flat fee of $49 per month.*

Prescription Care works directly with healthcare providers to help eligible individuals enroll in patient assistance programs for prescription medications. This includes the Jakafi patient assistance program. We handle the full enrollment process on your behalf. Prescription Care assists you to get easy and affordable access to the medication you need.

Your monthly Jakafi cost savings if eligible

If you are eligible for the Jakafi patient assistance program, you could receive your prescription medication for a flat fee of $49 per month. Each month you are in the program, you could save:

$2,300.00
Average 30-day price
at US Pharmacy
$49.00
Your 30-day price
at Prescription Care
$2,251.00
Your 30-day savings
with Prescription Care
$6,900.00
Average 30-day price
at US Pharmacy
$49.00
Your 30-day price
at Prescription Care
$6,851.00
Your 30-day savings
with Prescription Care
$6,900.00
Average 30-day price
at US Pharmacy
$49.00
Your 30-day price
at Prescription Care
$6,851.00
Your 30-day savings
with Prescription Care
$6,900.00
Average 30-day price
at US Pharmacy
$49.00
Your 30-day price
at Prescription Care
$6,851.00
Your 30-day savings
with Prescription Care
$6,900.00
Average 30-day price
at US Pharmacy
$49.00
Your 30-day price
at Prescription Care
$6,851.00
Your 30-day savings
with Prescription Care

Am I eligible for the Jakafi patient assistance program?

You will need to meet specific eligibility criteria to secure Jakafi assistance. Prescription Care will review each application individually. The main factors that are considered by most programs include:

  • US residency
  • Combined household income
  • Insurance status
General income criteria
  • Up to $36,000
  • Up to $50,000
  • Up to $100,000

How do I apply for the Jakafi patient assistance program? 

Our process makes it simple to apply for the Jakafi patient assistance program.

Begin by completing your enrollment application on our website. Let us know about any medications you’re taking, including Jakafi, as well as details about your healthcare provider, your insurance plan, and your household income.

Once we determine that you may be eligible for Jakafi assistance, we’ll handle the full enrollment process for you, and will request your Jakafi medication refills for up to one year.

Is Prescription Care a Jakafi coupons provider?

We are a service provider that helps eligible individuals access the Jakafi patient assistance program. We are not a Jakafi coupon, a Jakafi discount card, or a Jakafi copay card provider. Our service does not extend to the provision of Jakafi manufacturer coupons, Jakafi discounts, rebates, Jakafi savings cards, trial offers, or free Jakafi samples.

Can Prescription Care help me get Jakafi if I have insurance? 

You can apply online through Prescription Care for the Jakafi patient assistance program. You may be eligible for Jakafi assistance in the following scenarios: 

  • If your insurance company won’t pay for your prescription 
  • If you have a high copay or coinsurance responsibility 
  • If you don’t have insurance, or if your Medicare plan doesn’t cover Jakafi  

How much is Jakafi with insurance?

Jakafi medication costs will vary  with the terms of your healthcare plan. Contact your insurance provider or pharmacist to find out more. They will be able to calculate your copay with your current insurance.

How much does Jakafi cost without insurance?

Jakafi prices without insurance will vary depending on the quantity you buy and where you buy it from. As a guide, a pack of 30, 20 mg Jakafi tablets will usually cost around $8,100.

What is Jakafi?

Jakafi is a prescription medication used to treat:

  • Certain types of myelofibrosis in adults – a rare type of cancer that affects your bone marrow. 
  • Polycythemia vera (a condition where your bone marrow produces too many red blood cells) in adults. It is prescribed when a medication called hydroxyurea has already been taken but it didn’t work well enough or its side effects couldn’t be tolerated.  
  • Acute graft-versus-host disease in adults and children over 12 years old, who have already taken a corticosteroid but found it didn’t work well enough. 

Jakafi is a medication that can inhibit an enzyme in your body, called janus associated kinases (JAKs), that can cause and/or aggravate myelofibrosis, polycythemia vera, and acute graft-versus-host disease. It can reduce inflammation in your body caused by these conditions and can alleviate many of the other symptoms they cause.

Jakafi comes as an oral tablet. How many tablets you take and how often will be decided upon by your doctor based on your condition and medical history.

Jakafi active ingredients

The active ingredient in Jakafi is called ruxolitinib. When you take Jakafi, the ruxolitinib it contains binds with a type of enzyme in your body called janus associated kinases (JAKs).

These enzymes are used by your immune system to cause inflammation and they play a role in causing or worsening your condition. Myelofibrosis and polycythemia vera are associated with mutations in genes that make these JAK enzymes. Your condition may be caused by your JAK enzymes not working properly. By binding with JAK enzymes, ruxolitinib turns them off, reducing the effect they have on your body. This can reduce any inflammation caused by your condition, helping to provide relief from your symptoms. 

Jakafi side effects & Jakafi drug interactions

When Jakafi causes side effects, the most common include:

  • Headaches
  • Diarrhea
  • Dizziness
  • Fluid retention
  • An increased risk of mild infections
  • An increase in bruising

Other common, but potentially serious side effects include:

  • Low red blood cell counts that can cause anemia
  • Low blood platelet counts (thrombocytopenia) that can increase your risk of bleeding
  • Low white blood cell counts (neutropenia) that can weaken your immune system
  • An increased risk of serious infections

In rare instances, Jakafi can cause the following serious side effects:

  • Severe allergic reactions to the medication
  • An increased risk of developing non-melanoma skin cancers
  • An increase in blood cholesterol levels

Jakafi can interact with other medications, including:

  • Any medications that can increase your risk of bleeding, including warfarin (Coumadin or Jantoven), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen
  • Any medications taken to treat fungal infections, including ketoconazole, itraconazole, posaconazole, fluconazole, or voriconazole
  • Any antibiotics, including clarithromycin, telithromycin, ciprofloxacin, or erythromycin
  • Rifabutin or rifampicin, taken used to treat tuberculosis (TB)
  • Any medications taken to treat HIV/AIDS, like amprenavir, atazanavir, indinavir, lopinavir/ritonavir, nelfinavir, ritonavir, or saquinavir
  • Any anti-epilepsy medications taken to reduce seizures, like phenytoin, carbamazepine, or phenobarbital
  • Nefazodone, taken to treat depression
  • Mibefradil or diltiazem, taken to treat high blood pressure (hypertension) and chronic angina pectoris
  • Cimetidine, taken to treat heartburn
  • St. John’s wort (Hypericum perforatum), an herbal product taken to treat depression

Jakafi warnings & precautions

Don’t take Jakafi if you:

  • Are allergic to the active ingredient ruxolitinib
  • Are allergic to any of the other ingredients in Jakafi 
  • Are under 18 years of age for myelofibrosis or polycythemia vera
  • Are under 12 years of age for acute graft-versus-host disease

Talk to your doctor before taking Jakafi if you:

  • Have a current infection
  • Have, or have had, hepatitis B
  • Have, or have had, tuberculosis, or have been in close contact with someone who has
  • Have, or have had any liver problems
  • Have, or have had, any kidney problems or are on dialysis. If you are on dialysis, take your Jakafi after your dialysis
  • Have, or have had skin cancer
  • Have high levels of fat in your blood, like cholesterol or triglycerides
  • Are pregnant 
  • Are breastfeeding or are planning to breastfeed

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as Prescription Care assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (Refund).

To receive a Refund, you must send the letter of denial to us by fax to 866-262-2603, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.


Speak with a Patient Advocate

866-299-0857
Get Started